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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
29.09
Human Site:
Y458
Identified Species:
53.33
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
Y458
V
K
M
S
L
Q
L
Y
L
V
D
N
R
S
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
Y454
S
K
M
S
L
Q
L
Y
Q
V
D
S
R
T
Y
Dog
Lupus familis
XP_546691
722
81319
Y628
V
K
M
S
L
Q
L
Y
L
V
D
N
R
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
Y458
V
K
M
S
L
Q
L
Y
L
V
D
S
R
S
Y
Rat
Rattus norvegicus
Q09137
552
62239
Y458
V
K
M
S
L
Q
L
Y
L
V
D
N
R
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
Y423
S
K
M
S
L
Q
L
Y
Q
V
D
S
R
T
Y
Chicken
Gallus gallus
Q9IA88
798
88848
C673
H
Q
L
L
Q
P
A
C
P
Q
T
S
Q
T
S
Frog
Xenopus laevis
NP_001088426
560
64038
Y464
T
K
M
S
L
Q
L
Y
Q
V
D
S
R
T
Y
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
V796
V
T
I
Q
V
Q
E
V
E
L
G
G
G
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
N421
S
K
P
N
D
I
M
N
E
V
Y
R
A
M
K
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
Y522
P
K
M
S
L
Q
L
Y
Q
V
D
Q
R
S
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
C441
A
L
Q
D
L
N
V
C
W
K
K
I
G
H
Y
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L529
I
Y
I
A
L
K
N
L
G
A
E
W
A
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
73.3
100
N.A.
93.3
100
N.A.
73.3
0
73.3
13.3
N.A.
N.A.
13.3
80
N.A.
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
100
N.A.
86.6
33.3
86.6
40
N.A.
N.A.
26.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
0
8
0
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
62
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
16
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
8
8
16
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
16
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
70
0
0
0
8
0
0
0
8
8
0
0
8
8
% K
% Leu:
0
8
8
8
77
0
62
8
31
8
0
0
0
0
0
% L
% Met:
0
0
62
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
8
8
8
0
0
0
24
0
0
0
% N
% Pro:
8
0
8
0
0
8
0
0
8
0
0
0
0
0
8
% P
% Gln:
0
8
8
8
8
70
0
0
31
8
0
8
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
62
0
0
% R
% Ser:
24
0
0
62
0
0
0
0
0
0
0
39
0
39
8
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
8
0
0
31
0
% T
% Val:
39
0
0
0
8
0
8
8
0
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
62
0
0
8
0
0
0
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _